Epinerve-NT Tablets

Introduction

Epinerve-NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Epinerve-NT Tablet is taken by mouth, with or without food and preferably at bedtime. It is advisable to take it at the same time each day as this helps to maintain consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop this medication suddenly without talking to the doctor.

Some common side effects of this medicine include peripheral edema, dry mouth, difficulty in concentration, increased heart rate, constipation and blurred vision. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Uses of Epinerve-NT Tablet

Neuropathic pain

Side Effects of Epinerve-NT Tablet

• Constipation
• Difficulty in urination
• Weight gain
• Sleepiness
• Dizziness
• Tiredness
• Blurred vision
• Dryness in mouth
• Increased heart rate
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Uncoordinated body movements

How to Use Epinerve-NT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epinerve-NT Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Epinerve-NT Tablet Works

Epinerve-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha to delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety Advice

Alcohol

UNSAFE

Epinerve-NT Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Epinerve-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

Epinerve-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Epinerve-NT Tablet may cause side effects which could affect your ability to drive.

As Epinerve-NT Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Epinerve-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Epinerve-NT Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Epinerve-NT Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Epinerve-NT Tablet may not be needed in these patients. Please consult your doctor.